Antitumor Activity of Cordyceps militaris against Hepatitis C Virus-Infected Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Hepatitis C virus (HCV) often causes chronic hepatitis, which leads to liver cirrhosis and the development of HCC.

In 2015, the results of a study (Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells) were published in the Journal of Microbiology in which scientists from South Korea investigated the antitumor activity of ethanol extract of Cordyceps militaris (CME) on human hepatocellular carcinoma cells, including those infected with HCV.

Also check out Auricularia auricula-judae — a mushroom known to help with liver recovery:Auricularia auricula: Supporting the Liver after Alcohol-Related Damage

The studies showed that CME has potent antitumor activity against HCV-infected human hepatocellular carcinoma cells. Cordyceps suppresses the growth and proliferation of cancer cells, induces their death through apoptosis (programmed cell death), and reduces their size.

It was found that CME:

  • Effectively kills cancer cells, reducing their viability by 75-100%.
  • Triggers the apoptosis process - natural programmed cell death. Depending on the dose, it accumulates the early stage of apoptosis up to 6.78% of cancer cells.
  • Increases the number of special proteins (Bim, Bax, caspase-3, and caspase-9). These proteins are responsible for the activation of apoptosis and the death of cancer cells.
  • Reduces the number of viral proteins (Core and NS3) in cells infected with the hepatitis C virus. That is, it has an antiviral effect.
  • Suppresses tumor growth and promotes their size reduction compared to the control group.

We also recommend: Impact of Cordyceps militaris on Immunity

The results of the study suggest the feasibility of using CME for the prevention and to enhance the effectiveness of standard HCC treatment methods, especially those associated with HCV.

Cordyceps militaris has immunomodulatory, anti-inflammatory, antitumor, and antiviral effects, making it beneficial for your liver and protecting against the development of cancer. Take care of your health, take care of your loved ones, and take a course of Cordyceps militaris, because a healthy liver is the key to the health of the whole body!

Read about the immunomodulatory properties of mushrooms in the article "Liver Regeneration with the Help of Lion’s Mane Mushroom"

The article is based on a published scientific study in the Journal of Microbiology (2015) 53, 7, 468. For our regular customers, we can provide a printout of the translation of the article upon request.

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This information is provided for informational purposes only and is not medical advice. Consult your doctor before taking any supplements.

Frequently Asked Questions about Cordyceps militaris and the Liver

  1. Can Cordyceps militaris cure hepatitis C?
    No. It is not a medicine, but it may reduce viral activity and support the liver.

  2. What anticancer properties does Cordyceps militaris have?
    It may inhibit the growth of hepatocellular carcinoma cells, reduce inflammation, and activate the immune system.

  3. How should Cordyceps militaris be taken for liver health?
    The most effective are standardized extracts in capsules. The recommended course is 1 to 3 months.

  4. Is Cordyceps militaris safe for long-term use?
    Yes, at recommended doses it is well tolerated, but it is advisable to consult a doctor before starting the course.

For each client individually, we draw up instructions according to his indicators and requests

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